Nasal positive pressure with the SuperNO 2 VA™ device decreases sedation-related hypoxemia during pre-bariatric surgery EGD

Surg Endosc. 2019 Nov;33(11):3828-3832. doi: 10.1007/s00464-019-06721-1. Epub 2019 Feb 25.

Abstract

Introduction: Pre-operative esophagogastroduodenoscopy (EGD) is becoming routine practice in patients undergoing bariatric surgery. Many patients with morbid obesity have obstructive sleep apnea (OSA), which can worsen hypoxia during an EGD. In this study, we report our outcomes using the SuperNO2VA™ device, a sealed nasal positive airway pressure mask designed to deliver high-fraction inhaled oxygen and titratable positive pressure compared to conventional nasal cannula.

Methods: Between June 2016 and August 2017, we conducted a prospective observational study that included 56 consecutive patients who presented for EGD prior to bariatric surgery. Airway management was done using either the SuperNO2VA™ (N = 26) device or conventional nasal cannula (N = 30). Patient demographics, procedure details, and outcomes were compared between the two groups.

Results: The SuperNO2VA™ group had a lower median age compared to the control group (38.5 vs. 48.5 years, p = 0.04). These patients had a higher body mass index (BMI) (47.4 vs. 40.5, IQR, p < 0.0001), higher ASA class (p = 0.03), and were more likely to have OSA (53.9% vs. 26.7%, p = 0.04). Desaturation events were significantly lower in the SuperNO2VA™ group (11.5% vs. 46.7%, p = 0.004) and the median lowest oxygen saturation was higher in the SuperNO2VA™ group (100% vs. 90.5%, p < 0.0001).

Discussion: This is the first study to report on the use of the SuperNO2VA™ device in bariatric patients undergoing pre-operative screening EGD. The use of the SuperNO2VA™ device offers a clinical advantage compared to the current standard of care. Our data demonstrate that patients with higher BMI, higher ASA classification, and OSA were more likely to have the SuperNO2VA™ device used; yet, paradoxically, these patients were less likely to have issues with desaturation events. Use of this device can optimize care in this challenging patient population by minimizing the risks of hypoventilation.

Keywords: Bariatric surgery; Endoscopy; Hypoxemia; Obesity; Obstructive sleep apnea.

MeSH terms

  • Adult
  • Bariatric Surgery / methods
  • Endoscopy, Digestive System* / adverse effects
  • Endoscopy, Digestive System* / methods
  • Female
  • Humans
  • Hypoxia* / etiology
  • Hypoxia* / prevention & control
  • Male
  • Masks
  • Middle Aged
  • Obesity, Morbid* / complications
  • Obesity, Morbid* / surgery
  • Outcome Assessment, Health Care
  • Oxygen Inhalation Therapy* / instrumentation
  • Oxygen Inhalation Therapy* / methods
  • Preoperative Care / methods
  • Prospective Studies
  • Sleep Apnea, Obstructive / complications