Abstract
Fetal exposure to valproic acid has recently been associated with an increased incidence of neural tube defects. The prenatal detection of a fetus with both hydrocephalus and meningomyelocele after valproic acid exposure is presented and specific recommendations made for antepartum evaluation in future pregnancies.
MeSH terms
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Abortion, Therapeutic
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Adolescent
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Epilepsy / complications
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Epilepsy / drug therapy
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Female
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Fetal Diseases / chemically induced*
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Fetal Diseases / diagnosis
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Humans
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Hydrocephalus / chemically induced
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Hydrocephalus / diagnosis
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Meningomyelocele / chemically induced
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Meningomyelocele / diagnosis
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Neural Tube Defects / chemically induced*
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Neural Tube Defects / diagnosis
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Pregnancy
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Pregnancy Complications*
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Prenatal Diagnosis*
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Valproic Acid / adverse effects*
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Valproic Acid / therapeutic use