Prenatal detection of a neural tube defect after fetal exposure to valproic acid

Obstet Gynecol. 1986 Mar;67(3 Suppl):31S-33S. doi: 10.1097/00006250-198603001-00009.

Abstract

Fetal exposure to valproic acid has recently been associated with an increased incidence of neural tube defects. The prenatal detection of a fetus with both hydrocephalus and meningomyelocele after valproic acid exposure is presented and specific recommendations made for antepartum evaluation in future pregnancies.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Therapeutic
  • Adolescent
  • Epilepsy / complications
  • Epilepsy / drug therapy
  • Female
  • Fetal Diseases / chemically induced*
  • Fetal Diseases / diagnosis
  • Humans
  • Hydrocephalus / chemically induced
  • Hydrocephalus / diagnosis
  • Meningomyelocele / chemically induced
  • Meningomyelocele / diagnosis
  • Neural Tube Defects / chemically induced*
  • Neural Tube Defects / diagnosis
  • Pregnancy
  • Pregnancy Complications*
  • Prenatal Diagnosis*
  • Valproic Acid / adverse effects*
  • Valproic Acid / therapeutic use

Substances

  • Valproic Acid