Mesolimbic dopamine and anterior cingulate cortex connectivity changes lead to impulsive behaviour in Parkinson's disease

Antonio P Strafella

doi:10.1093/brain/awz010

Mesolimbic dopamine and anterior cingulate cortex connectivity changes lead to impulsive behaviour in Parkinson's disease

Brain. 2019 Mar 1;142(3):496-498. doi: 10.1093/brain/awz010.

Author

Antonio P Strafella^{1

2

3}

Affiliations

¹ The Edmond J. Safra Program in Parkinson's Disease and Movement Disorder Unit, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada.
² Krembil Research Institute, University Health Network, University of Toronto, Ontario, Canada.
³ Research Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada.

Abstract

This scientific commentary refers to ‘Dopamine metabolism of the nucleus accumbens and fronto-striatal connectivity modulate impulse control’, by Hammes et al. (doi:10.1093/brain/awz007).

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Dopamine*
Gyrus Cinguli
Humans
Impulsive Behavior
Nucleus Accumbens
Parkinson Disease*

Substances

Dopamine

Grants and funding

MOP-136778/CIHR/Canada