Quantitative Analysis of Objective Forward Scattering and Its Relevant Factors in Eyes with Cataract

Sci Rep. 2019 Feb 28;9(1):3167. doi: 10.1038/s41598-019-39680-7.

Abstract

This study was aimed to quantitatively assess objective forward scattering and its relevant factors in eyes having cataract. Our study comprised 192 eyes of 192 patients (mean age, 71.3 ± 9.2 (standard deviation) years) who have cataract formation for surgical consultation. We determined uncorrected and corrected distance visual acuities (UDVA and CDVA), manifest refraction, the grade of nuclear sclerosis, objective scattering index (OSI) with the OQAS II (Visiometrics, Spain), log(s) with the C-Quant (Oculus, Germany), and ocular higher-order aberrations (HOAs) using the wavefront sensor (KR-1W, Topcon, Japan). The mean OSI was 5.11 ± 3.19 (0.90 to 20.90). We found explanatory variables relevant to the OSI to be, logMAR CDVA (p < 0.0001, partial regression coefficient B = 5.917) and log(s) (p = 0.0006, B = 0.911) (adjusted R2 = 0.333), in order of influence. No significant correlation was found with other clinical factors such as gender, age, manifest refraction, UDVA, ocular HOAs, or nuclear sclerosis. Eyes with worse CDVA and higher log(s) are more predisposed to show higher OSI in cataractous eyes. It is suggested that objective forward scattering was associated, not only with CDVA, but also with subjective forward scattering, in cataractous subjects.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cataract / diagnosis*
  • Cataract / diagnostic imaging
  • Cataract / pathology
  • Cornea / diagnostic imaging
  • Cornea / pathology
  • Corneal Wavefront Aberration / diagnosis*
  • Corneal Wavefront Aberration / diagnostic imaging
  • Corneal Wavefront Aberration / pathology
  • Female
  • Germany
  • Humans
  • Japan
  • Male
  • Middle Aged
  • Refraction, Ocular / physiology
  • Scattering, Radiation
  • Spain
  • Visual Acuity*

Supplementary concepts

  • Cataract, Age-Related Nuclear