High-flow Nasal Cannula Versus Noninvasive ventilation for Postextubation Acute Respiratory Failure after Pediatric Cardiac Surgery

Acta Med Okayama. 2019 Feb;73(1):15-20. doi: 10.18926/AMO/56454.

Abstract

We compared the reintubation rate in children who received high-flow nasal cannula (HFNC) therapy to the rate in children who received noninvasive ventilation (NIV) therapy for acute respiratory failure (ARF) after cardiac surgery. This was a retrospective analysis of 35 children who received HFNC therapy for ARF after cardiac surgery in 2014-2015 (the HFNC group). We selected 35 children who had received NIV therapy for ARF after cardiac surgery in 2009-2012 as a control group. The matching parameters were body weight and risk adjustment for congenital heart surgery category 1. The reintubation rate within 48 h in the HFNC group tended to be lower than that in the NIV group (3% vs. 17%, p=0.06). The reintubation rate within 28 days was significantly lower in the HFNC group compared to the NIV group (3% vs. 26%, p=0.04). The HFNC group's ICU stays were significantly shorter than those of the NIV group: 10 (IQR: 7-17) days vs. 17 (11-32) days, p=0.009. HFNC therapy might be associated with a reduced reintubation rate in children with ARF after cardiac surgery.

Keywords: acute respiratory failure; congenital heart disease; high-flow nasal cannula; noninvasive ventilation; reintubation.

Publication types

  • Comparative Study

MeSH terms

  • Airway Extubation / adverse effects*
  • Cannula*
  • Cardiac Surgical Procedures / adverse effects*
  • Case-Control Studies
  • Female
  • Humans
  • Infant
  • Intubation, Intratracheal
  • Male
  • Noninvasive Ventilation*
  • Oxygen Inhalation Therapy
  • Respiratory Insufficiency / etiology
  • Respiratory Insufficiency / therapy*
  • Retrospective Studies
  • Treatment Outcome