Abstract
The role of the mast cell in ocular allergy is becoming understood. As a result, the therapeutic effects of agents that stabilize the mast cell have been evaluated in the treatment of seasonal allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, and giant papillary conjunctivitis. At present, cromolyn sodium is the only available mast cell stabilizer of known effectiveness. Clinical and laboratory investigations of the effectiveness of cromolyn sodium in the treatment of ocular allergy are reviewed in the present article.
Publication types
-
Clinical Trial
-
Research Support, U.S. Gov't, P.H.S.
-
Review
MeSH terms
-
Anaphylaxis / etiology
-
Biomechanical Phenomena
-
Clinical Trials as Topic
-
Conjunctivitis, Allergic / drug therapy
-
Conjunctivitis, Allergic / pathology
-
Conjunctivitis, Allergic / physiopathology
-
Cromolyn Sodium / therapeutic use
-
Endophthalmitis / pathology
-
Endophthalmitis / physiopathology
-
Eye Diseases / drug therapy*
-
Eye Diseases / pathology
-
Eye Diseases / physiopathology
-
Humans
-
Hypersensitivity / drug therapy*
-
Hypersensitivity / pathology
-
Hypersensitivity / physiopathology
-
Keratoconjunctivitis / classification
-
Keratoconjunctivitis / drug therapy
-
Keratoconjunctivitis / pathology
-
Mast Cells / drug effects*
-
Mast Cells / physiology
-
Seasons