[The differentiated diagnostic of chronic salpingoophoritis and ovary cancer on the basis of immunologic and discriminant techniquea]

Klin Lab Diagn. 2017;62(10):611-615. doi: 10.18821/0869-2084-2017-62-10-611-615.
[Article in Russian]

Abstract

The ovary cancer and chronic salpingoophoritis are among leading pathologies of female's sexual sphere and a main cause of morbidity and mortality of female population. The purpose of study was to select leading differential diagnostic indices of systemic cellular immunity and to carry out a differentiation of patients with ovary cancer and chronic salpingoophoritis using discriminant technique. The differentiated diagnostic of ovary cancer and chronic salpingoophoritis was applied to 92 and 87 patients correspondingly to indices of systemic cellular immunity and analyzed by flow cytometry technique. It is demonstrated that the main differential diagnostic indices of systemic cellular immunity in case of ovary cancer and chronic salpingoophoritis are decreasing of relative content of natural killers, absolute number of B-lymphocytes and T-helpers. The developed discriminant models permit to carry out in 91.8%-92.1% cases a faultless differentiated diagnostic of ovary cancer and chronic salpingoophoritis. The approach like that increases quality of differentiated diagnostic of ovary cancer and chronic salpingoophoritis.

Keywords: chronic salpingoophoritis; differentiated diagnostic; discriminant technique; flow cytometry technique; ovary cancer; systemic cellular immunity.

Publication types

  • English Abstract