Dermal nerve sheath myxoma: a study of three cases

Histopathology. 1986 Feb;10(2):135-45. doi: 10.1111/j.1365-2559.1986.tb02469.x.


Three cases of dermal nerve sheath myxoma have been studied by light microscopy, histochemistry and immunohistochemistry. The pertinent literature has been reviewed. This lesion, which is a rare benign tumour of probable nerve sheath origin, arises most often in young adults and shows a predeliction for females. Histologically it has a characteristic appearance. Histochemically, the heteroglycan content of the mucoid matrix is more in keeping with a cartilaginous lesion. The histogenesis and differential diagnosis are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chondroitin Sulfates / analysis
  • Female
  • Histocytochemistry
  • Humans
  • Immunoenzyme Techniques
  • Male
  • Middle Aged
  • Myxoma / analysis
  • Myxoma / pathology*
  • Peripheral Nervous System Neoplasms / analysis
  • Peripheral Nervous System Neoplasms / pathology*
  • Polysaccharides / analysis
  • S100 Proteins / analysis
  • Skin / innervation
  • Skin Neoplasms / analysis
  • Skin Neoplasms / pathology*


  • Polysaccharides
  • S100 Proteins
  • Chondroitin Sulfates