Intracranial Vascular Responses to High-Intensity Interval Exercise and Moderate-Intensity Steady-State Exercise in Children

Pediatr Exerc Sci. 2019 Aug 1;31(3):290-295. doi: 10.1123/pes.2018-0234.

Abstract

Purpose: To understand the extent different types of acute exercise influence cerebral blood flow during and following exercise in children.

Methods: Eight children (7-11 y; 4 girls) completed 2 conditions: high-intensity interval exercise (HIIE; 6 × 1-min sprints at 90% watt maximum) and moderate-intensity steady-state exercise (MISS; 15 min at 44% watt maximum). Blood velocity in the middle cerebral artery (MCAV) and heart rate were assessed continuously. The partial pressure of end-tidal carbon dioxide and mean arterial pressure were assessed at baseline and following exercise.

Results: Percentage of maximum heart rate during HIIE was 82% (4%), compared with 69% (4%) during MISS. MCAV was increased above baseline in MISS after 75 seconds (5.8% [3.9%], P × .004) but was unchanged during HIIE. MCAV was reduced below baseline (-10.7% [4.1%], P × .004) during the sixth sprint of HIIE. In both conditions, MCAV remained below baseline postexercise, but returned to baseline values 30-minute postexercise (P < .001). A postexercise increase in mean arterial pressure was apparent following HIIE and MISS, and persisted 30-minute postexercise. Partial pressure of end-tidal carbon dioxide declined post HIIE (-3.4 mm Hg, P < .05), but not following MISS.

Conclusion: These preliminary findings show HIIE and MISS elicit differing intracranial vascular responses; however, research is needed to elucidate the implications and underlying regulatory mechanisms of these responses.

Keywords: cerebrovascular; end-tidal carbon dioxide; exercise intensity; middle cerebral artery.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Flow Velocity*
  • Blood Pressure
  • Child
  • Cross-Over Studies
  • Exercise*
  • Female
  • Heart Rate
  • High-Intensity Interval Training*
  • Humans
  • Male
  • Middle Cerebral Artery / physiology*
  • Partial Pressure