Biomimetic Enhancement of Bone Graft Reconstruction

Oral Maxillofac Surg Clin North Am. 2019 May;31(2):193-205. doi: 10.1016/j.coms.2018.12.001. Epub 2019 Mar 2.


With aging populations and increasing oral rehabilitation, use of dental implants for oral reconstruction is increasing. Adequate hard/soft tissue are required to support use of titanium implants. Bone augmentation is sometimes a necessary procedure to supplement existing alveolar bone. With a wide variety of biomaterials available for clinical use, we focus on the enhancement of bone graft materials, targeting new technologies with potential clinical use. Clinical indications supported by research studies are provided for platelet-rich fibrin, various growth factors, and newly emerging scaffolds. Interestingly, modified biomaterials are being developed and have potential clinical use as more data become available.

Keywords: Biomimetic enhancement; Bone augmentation; Bone grafting; Growth factors; Scaffolds.

Publication types

  • Review

MeSH terms

  • Alveolar Ridge Augmentation*
  • Biomimetics*
  • Bone Transplantation / methods*
  • Dental Implantation, Endosseous
  • Dental Implants*
  • Humans
  • Maxilla / surgery*


  • Dental Implants