Finasteride for androgenetic alopecia is not associated with sexual dysfunction: a survey-based, single-centre, controlled study

J Eur Acad Dermatol Venereol. 2019 Jul;33(7):1393-1397. doi: 10.1111/jdv.15548. Epub 2019 Apr 15.

Abstract

Background: The occurrence of sexual dysfunction side-effects associated with finasteride use in men with androgenetic alopecia (AGA) is thought to be less prevalent than is publicized. There is a need to investigate sexual dysfunction among finasteride users with population-based controls.

Objective: To evaluate the presence of sexual dysfunction in men using finasteride or not using finasteride.

Method: Adult men visiting a dermatologist's office for any reason were asked to complete a survey including a modified version of the Arizona Sexual Experience Scale (ASEX) to assess the presence of sexual dysfunction with and without finasteride use.

Results: Data from 762 men aged 18-82 were collected: 663 finasteride users and 99 non-finasteride users. There were no significant differences between finasteride users and non-user controls in reporting sexual dysfunction using the ASEX. Regression analysis indicated that self-reporting libido loss and reduced sexual performance, not finasteride use, predict a higher ASEX score.

Conclusion: The use of finasteride does not result in sexual dysfunction in men with AGA. These data are consistent with other large survey-based controlled studies.

MeSH terms

  • Adolescent
  • Adult
  • Alopecia / drug therapy*
  • Case-Control Studies
  • Dermatologic Agents / adverse effects*
  • Finasteride / adverse effects*
  • Humans
  • Libido
  • Middle Aged
  • Sexual Dysfunction, Physiological / chemically induced*
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Dermatologic Agents
  • Finasteride