Targeting proprotein convertase subtilisin/kexin type 9 in mice and monkeys

Curr Opin Lipidol. 2019 Apr;30(2):154-155. doi: 10.1097/MOL.0000000000000583.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Atherosclerosis / genetics
  • Atherosclerosis / metabolism
  • Atherosclerosis / pathology
  • Atherosclerosis / therapy*
  • Cholesterol / blood
  • Dependovirus / genetics*
  • Dependovirus / metabolism
  • Disease Models, Animal
  • Female
  • Genetic Vectors / administration & dosage
  • Genetic Vectors / chemistry
  • Genetic Vectors / metabolism
  • Humans
  • Hypercholesterolemia / genetics
  • Hypercholesterolemia / metabolism
  • Hypercholesterolemia / pathology
  • Hypercholesterolemia / therapy*
  • Macaca mulatta
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Molecular Targeted Therapy / methods
  • Proprotein Convertase 9 / antagonists & inhibitors
  • Proprotein Convertase 9 / genetics*
  • Proprotein Convertase 9 / metabolism
  • Receptors, LDL / deficiency
  • Receptors, LDL / genetics*

Substances

  • Receptors, LDL
  • Cholesterol
  • Proprotein Convertase 9