Mapping In Vivo RNA Structures and Interactions

Trends Biochem Sci. 2019 Jun;44(6):555-556. doi: 10.1016/j.tibs.2019.01.012. Epub 2019 Mar 7.


RNA folds to form diverse secondary and tertiary structures and often interacts with other biomolecules to function in cells. The technologies developed to map in vivo RNA structures and interactions can be broadly classified into four categories.

Keywords: RNA interactions; RNA structure; mass spectroscopy; next-generation sequencing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry
  • Nucleic Acid Conformation
  • RNA / chemistry*
  • Sequence Analysis, RNA*


  • RNA
  • DNA