In Vivo Analysis of Embryo Development and Behavioral Response of Medaka Fish under Static Magnetic Field Exposures

Int J Environ Res Public Health. 2019 Mar 8;16(5):844. doi: 10.3390/ijerph16050844.


The static magnetic field (SMF) in human exposure has become a health risk concern, especially with respect to prolonged exposure. The International Commission on Non-Ionizing Radiation Protection (ICNIRP) has been considering cell or animal models to be adopted to estimate the possible human health impacts after such exposure. The medaka fish is a good animal model for human-related health assessment studies; this paper examines both the embryo development and behavioral responses in medaka fish in vivo to long-term SMF exposure at the mT level. SMF exposure was examined for the complete developmental period of embryos until hatched; the embryos were monitored and recorded every 24 h for different morphological abnormalities in their developmental stages. The behavioral response of adult fish was also examined by analyzing their swimming velocities and positioning as compared with that of the control group. It was observed that there were no impacts on embryo development under prolonged exposure up to about 100 mT while the swimming behavior of the adult fish under exposure was different to the control group-the swimming movement of the treated group was more static, with an average velocity of 24.6% less as observed over a 24-h duration.

Keywords: behavioral response; embryo development; in vivo; medaka fish; static magnetic field.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Behavior, Animal / radiation effects*
  • Embryonic Development / radiation effects*
  • Humans
  • Magnetic Fields*
  • Models, Animal
  • Oryzias / embryology*
  • Oryzias / physiology*
  • Swimming