Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 7 (1)

Regeneration of the Periodontal Apparatus in Aggressive Periodontitis Patients

Affiliations
Review

Regeneration of the Periodontal Apparatus in Aggressive Periodontitis Patients

Zvi Artzi et al. Dent J (Basel).

Abstract

The purpose of this study is to evaluate and compare, retrospectively, the outcome of two different periodontal regeneration procedures in patients suffering from aggressive periodontitis (AgP). Twenty-eight patients were diagnosed with AgP, suffering from several intra-bony defects (IBD); that were treated by one of two periodontal regeneration techniques randomly assigned to each patient: a. guided tissue regeneration (GTR) or b. an application of extracted enamel matrix derivatives (EMD) combined with demineralized bone xenograft particles (DBX). Probing pocket depth (PPD), clinical attachment level (CAL), and gingival recession were recorded. Pre-treatment and follow-up (up to 10 years from the surgery) recordings were analyzed statistically within and between groups. A significant reduction was shown at time on PPD and CAL values, however, not between subject groups. CAL values decreased in all sites. At the EMD group (44 sites), CAL gain was 1.92 mm (±1.68) from pre-treatment to follow-up (p < 0.001) and at the GTR group (12 sites) CAL gain of 2.27 (±1.82) mm. In conclusion, 1⁻10 years observations have shown that surgical treatment of AgP patients by either GTR or by application of EMD/DBX results in similar successful clinical results.

Keywords: aggressive periodontitis; deproteinized bovine bone; enamel matrix derivatives (Emdogain®); guided tissue regeneration (GTR); periodontal regeneration.

Conflict of interest statement

The authors declare no conflict of interest

Figures

Figure 1
Figure 1
Case # 4 of the guided tissue regeneration (GTR) group, upper left sextant. The pre surgery periapical radiograph (a) demonstrates an extensive periodontal destruction around on the mesial aspect of the first molar. (b) The periodontal probe shows a 2-wall intrabony component of 7mm, which was filled by bovine bone mineral particles (c) and covered by a collagen membrane (d). two years follow-up periapical radiograph (e) shows bone filling around on the first molar.
Figure 2
Figure 2
Case # 4 of the GTR group, upper right sextant. (a,b) Buccal and palatal view of the crestal bone topography. BBM particles inserted to fill the defects (c) followed by overlay resorbable collagen membranes (d).
Figure 3
Figure 3
Case # 2 of the enamel matrix derivatives (EMD) group, upper right sextant. Pre surgery periapical radiograph (a) shows an extensive periodontal destruction around on the distal aspect of the first molar. Buccal (b) and palatal (c) aspects of the debrided roots. EMD gel was applied along the exposed roots (d) followed by BBM particles as a bio-material filler (e). four years follow-up periapical radiograph (f) shows bone filling around the first molar.
Figure 4
Figure 4
Case # 2 of the EMD group, lower right sextant. Papillary preserve technique flap elevation technique (a,b) performed to exposed the periodontal defect (c). EMD gel was applied on the debrided roots followed by BBM particles (d). In order to obtain full soft tissue closure the flaps were sutured (e). At 1 month, immaculate healing was evident (f). In order to achieve full closure, note the preservation performed of the interproximal col tissue (b), subsequently.
Figure 5
Figure 5
The pre (a) and post (b) periapical radiographs of Case #2 of the EMD group, lower right first molar. Note the bone filling on the mesial and distal aspect of the lower right first molar.

Similar articles

See all similar articles

References

    1. Albandar J.M. Aggressive periodontitis: Case definition and diagnostic criteria. Periodontology. 2000;65:13–26. doi: 10.1111/prd.12014. - DOI - PubMed
    1. Armitage G.C. Development of a classification system for periodontal diseases and conditions. Ann. Periodontol. 1999;4:1–6. doi: 10.1902/annals.1999.4.1.1. - DOI - PubMed
    1. Baer P.N. The case for periodontosis as a clinical entity. J. Periodontol. 1971;42:516–520. doi: 10.1902/jop.1971.42.8.516. - DOI - PubMed
    1. Baer P.N., Socransky S.S. Periodontosis: Case report with long-term follow-up. Periodontal Case Rep. 1979;1:1–6. - PubMed
    1. Hørmand J., Frandsen A. Juvenile periodontitis. Localization of bone loss in relation to age, sex, and teeth. J. Clin. Periodontol. 1979;6:407–416. doi: 10.1111/j.1600-051X.1979.tb01939.x. - DOI - PubMed
Feedback