Leukocytoclastic vasculitis after vaccination in a patient with inflammatory bowel disease

Rev Esp Enferm Dig. 2019 May;111(5):402-404. doi: 10.17235/reed.2019.5963/2018.


Patients with inflammatory bowel disease are likely to receive immunomodulation treatment and therefore, should be properly vaccinated. Despite their proven safety, vaccines are not exempt from adverse reactions. The clinical case was a young female with ulcerative colitis under mesalazine treatment, who developed leukocytoclastic vasculitis following vaccination for pneumococci, varicella and hepatitis A. This adverse reaction after the previously mentioned vaccines is barely described in the literature and has never been reported in a patient with an underlying condition.

Publication types

  • Case Reports

MeSH terms

  • Chickenpox Vaccine / adverse effects*
  • Colitis, Ulcerative / complications*
  • Female
  • Hepatitis A Vaccines / adverse effects*
  • Humans
  • Pneumococcal Vaccines / adverse effects*
  • Vasculitis, Leukocytoclastic, Cutaneous / etiology*
  • Young Adult


  • Chickenpox Vaccine
  • Hepatitis A Vaccines
  • Pneumococcal Vaccines

Supplementary concepts

  • Erythema elevatum diutinum