Drug Induced Gingival Overgrowth

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan.


Drug-induced gingival overgrowth (DIGO), also referred to as drug-induced gingival enlargement, and previously known as drug-induced gingival hyperplasia, is a side-effect of certain drugs where the gingival tissue is not the intended target organ. The key offending drug classes are anticonvulsants, immunosuppressants, and calcium channel blockers . Gingival overgrowth impedes proper dental hygiene and, apart from the cosmetic damage, causes painful chewing and eating. Therefore, patient education and information about the condition and its management are essential.

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