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. 2019 Feb;24(9):1900124.
doi: 10.2807/1560-7917.ES.2019.24.9.1900124.

Novel influenza A(H1N2) seasonal reassortant identified in a patient sample, Sweden, January 2019

Åsa Wiman  1   2 , Theresa Enkirch  1   2 , AnnaSara Carnahan  3 , Blenda Böttiger  4 , Tove Samuelsson Hagey  1 , Per Hagstam  5 , Rosmarie Fält  5 , Mia Brytting  1
Affiliations

Novel influenza A(H1N2) seasonal reassortant identified in a patient sample, Sweden, January 2019

Åsa Wiman et al. Euro Surveill. 2019 Feb.

Abstract

In January 2019, a human seasonal reassortant influenza A(H1N2) virus with a novel 7:1 genetic constellation was identified in a 68-year-old female patient with suspected pneumonia. The virus harboured A(H3N2) neuraminidase and remaining genes from A(H1N1)pdm09. The patient recovered after severe illness. No additional cases have been detected. This is the second identified A(H1N2) seasonal reassortant in a human in Europe within 1 year; a previous case was detected in the Netherlands in March 2018.

Keywords: Sweden; haemagglutinin; human influenza; neuraminidase; reassortant viruses; surveillance; whole genome sequencing.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Weekly number of positive influenza A virus samples, by subtype from sentinel surveillance and incidence of laboratory-confirmed influenza A in Sweden and Skåne County, week 40 2018–week 5 2019
Figure 2
Figure 2
Phylogenetic analysis of influenza A(H1N2) virus A/Ystad/1/2018 haemagglutinin (HA) genome segmenta
Figure 3
Figure 3
Phylogenetic analysis of the influenza A(H1N2) virus A/Ystad/1/2018 neuraminidase (NA) genome segmenta
See this image and copyright information in PMC

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