Primary leiomyosarcoma of the colon: a case report and review of the literature

Acta Chir Belg. 2020 Oct;120(5):353-356. doi: 10.1080/00015458.2019.1589185. Epub 2019 Mar 18.


Introduction: Primary leiomyosarcoma (LMS) of the colon is a rare and aggressive gastrointestinal tract tumor, associated with poor prognosis.Case presentation and methods: We present the case of an asymptomatic patient who was diagnosed with a low sigmoidal stricture on routine colonoscopy. Although biopsies were inconclusive, an oncological partial mesorectal excision (PME) was performed due to the malignant macroscopic aspect. Pathological examination surprisingly revealed a LMS. The patient received no adjuvant chemo- or radiotherapy, but is seen on regular follow-up. We review the literature on leiomyosarcoma of the colon: its diagnosis, treatment, and prognosis.Results: Up until now the patient shows no sign of recurrence, 15 months postoperatively.Conclusion: Radical resection is the treatment of choice for primary leiomyosarcoma of the colon and long-term follow-up is needed to evaluate metastatic disease or local recurrence.

Keywords: Leiomyosarcoma; colon; gastrointestinal; sarcoma; surgery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Colonic Neoplasms / diagnosis*
  • Colonic Neoplasms / therapy*
  • Colonoscopy
  • Humans
  • Leiomyosarcoma / diagnosis*
  • Leiomyosarcoma / therapy*
  • Male
  • Middle Aged