Neuropeptide-FMRFamide-like immunoreactivity in Drosophila: development and distribution

J Comp Neurol. 1986 May 22;247(4):430-8. doi: 10.1002/cne.902470403.

Abstract

Neuropeptide-FMRFamide-like immunoreactivity was characterized in the fruit fly, Drosophila melanogaster. In the adult central nervous system, a stereotypic pattern of immunoreactive cell bodies and immunoreactive nerve processes and varicosities was observed, indicating a neurochemical role for FMRFamide-like substance(s) in Drosophila. Localization of immunoreactivity in the central nervous system of early larval stage revealed that the majority of the prominent FMRFamide-like immunoreactive neurons were already differentiated. The FMRFamide-like immunoreactive neurons remain immunoreactive throughout postembryonic stage and persist in the adult central nervous system. In the larva, in addition to the central nervous system, FMRFamide-like immunoreactivity was localized in the fibers innervating the ring gland, in the ganglion innervating the gut and in the gastric caeca.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Drosophila melanogaster
  • FMRFamide
  • Fluorescent Antibody Technique
  • Ganglia / growth & development
  • Ganglia / metabolism
  • Larva
  • Metamorphosis, Biological*
  • Nervous System / metabolism*
  • Oligopeptides / metabolism*

Substances

  • Oligopeptides
  • FMRFamide