Synchronous primary cancers: Renal cell carcinoma and rectal cancer

J Cancer Res Ther. 2019 Jan-Mar;15(1):250-251. doi: 10.4103/jcrt.JCRT_45_17.

Abstract

Although cancers of rectum and kidney are common malignancies, the occurrence of primary synchronous neoplasms of these organs has been reported rarely. Very few case reports are available in literature till date. The relationship between these two events remains unclear, probably because of the rarity of the association. In this report, we describe incidentally detected renal cell carcinoma in an elderly man, during staging workup of rectal adenocarcinoma and both malignancies were surgically managed simultaneously with curative intent.

Keywords: Clear cell carcinoma; double primary; multiple malignancies; renal cell carcinoma with rectal cancer.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Renal Cell / diagnosis
  • Carcinoma, Renal Cell / pathology
  • Carcinoma, Renal Cell / therapy*
  • Chemoradiotherapy, Adjuvant / methods
  • Fluorouracil / therapeutic use
  • Humans
  • Kidney Neoplasms / diagnosis
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / therapy*
  • Leucovorin / therapeutic use
  • Male
  • Middle Aged
  • Neoplasms, Multiple Primary / diagnosis
  • Neoplasms, Multiple Primary / pathology
  • Neoplasms, Multiple Primary / therapy*
  • Nephrectomy
  • Organoplatinum Compounds / therapeutic use
  • Proctectomy
  • Rectal Neoplasms / diagnosis
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / therapy*
  • Treatment Outcome

Substances

  • Organoplatinum Compounds
  • Leucovorin
  • Fluorouracil

Supplementary concepts

  • Folfox protocol