Prolonged Shedding of Zika Virus RNA in Vaginal Secretions, Nicaragua

Emerg Infect Dis. 2019 Apr;25(4):808-810. doi: 10.3201/eid2504.180977.


Zika virus, an arthropod-borne flavivirus pathogen in humans, is unusual because it can be sexually transmitted and can be shed for prolonged periods in semen. We report viral shedding in vaginal secretions for up to 6 months, indicating the potential for sexual and vertical transmission by infected women.

Keywords: Nicaragua; Zika virus; sexually transmitted diseases; shedding; transmission; vaginal secretions; viruses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Humans
  • Infectious Disease Transmission, Vertical
  • Nicaragua
  • RNA, Viral / isolation & purification*
  • Vagina / virology
  • Virus Shedding*
  • Zika Virus / isolation & purification*
  • Zika Virus Infection / transmission*
  • Zika Virus Infection / virology


  • RNA, Viral