A meta-analysis of randomized controlled trials of laughter and humour interventions on depression, anxiety and sleep quality in adults

J Adv Nurs. 2019 Nov;75(11):2435-2448. doi: 10.1111/jan.14000. Epub 2019 May 9.


Aim: To quantify the effect of laughter and humour interventions on depression, anxiety, and sleep quality in adults.

Design: A meta-analysis of randomized controlled trials.

Data sources: PubMed, Embase, PsycINFO, Web of Science, Cochrane Central Register of Controlled Trials, Chinese National Knowledge Infrastructure, Weipu, and Wanfang Data were searched from their inception up to December 2018.

Review methods: The reporting of this meta-analytical review was conducted according to the guidelines of the Cochrane Collaboration. Two reviewers selected the studies, extracted the data, and evaluated the risk of bias (Cochrane Collaboration bias assessment tool) of the included papers independently.

Results: Ten studies comprising 814 participants were included. Meta-analysis showed that these interventions significantly decreased adults' depression, anxiety, and improved their sleep quality. The results of subgroup analysis showed that depression benefits more from long-term laughter intervention.

Conclusions: This meta-analysis revealed that laughter and humour interventions are effective in relieving depression, anxiety, and improve sleep quality in adults. More studies with high quality and follow-up assessment should be conducted for future research.

Impact: This review synthesized current evidence using laughter and humour interventions to reduce negative emotion and promote better results in adults, especially with respect to target the applicability between different populations or intervention methods. In addition, humour and laughter interventions are safe, convenient, interesting and can promote interpersonal relationship in both patients and medical workers, which have great feasibility and potential to be used as an aspect of psychotherapy for clinical and nursing to improve well-beings in adults.

目的: 在于量化笑声和幽默干预措施对成年人抑郁、焦虑和睡眠质量的影响。 设计: 随机对照试验的荟萃分析。 资料来源: 从收录到2018年12月,搜索了PubMed、Embase、PsycINFO、Web of Science、Cochrane对照试验中心注册库、中国期刊全文数据库、维普资讯网和万方数据知识服务平台。 综述方法: 本次荟萃分析综述的汇报是根据Cochrane 协作组织的指导方针进行的。两名审查者选择了研究,提取了数据,并分别评价了纳入论文的偏倚风险(Cochrane 协作组织的偏倚评估工具)。 结果: 纳入了10项由814名参与者组成的研究。荟萃分析表明,这些干预措施显著降低了成年人的抑郁、焦虑,并改善了他们的睡眠质量。亚组分析的结果表明,长期的笑声干预措施对抑郁症更为大有裨益。 结论: 这项荟萃分析显示,笑声和幽默干预措施在缓解成年人的抑郁、焦虑和改善睡眠质量方面卓有成效。应为未来的研究开展更多高质量研究和随访评估。 影响: 这篇综述综合了当前的证据,即,使用笑声和幽默干预措施来减少负面情绪,促进更好地成人结果,特别是针对不同人群或干预方法之间的适用性。此外,幽默和笑声干预措施安全、方便、有趣,可以改善患者和医务工作者之间的人际关系,这具有很大的可行性和潜力,可以作为临床和护理心理治疗的一个方面来促进成年人的健康。.

Keywords: adults; anxiety; depression; humour; laughter; meta-analysis; nursing; sleep quality.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Adult
  • Anxiety / physiopathology
  • Anxiety / therapy*
  • Depression / physiopathology
  • Depression / therapy*
  • Humans
  • Laughter*
  • Randomized Controlled Trials as Topic*
  • Sleep*
  • Wit and Humor as Topic*