How the complex pharmacology of the fentanyls contributes to their lethality

Addiction. 2019 Sep;114(9):1524-1525. doi: 10.1111/add.14614. Epub 2019 Apr 17.
No abstract available

Keywords: fentanyl; heroin; muscle stiffness; naloxone; overdose; respiratory depression.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Overdose / drug therapy
  • Drug Overdose / mortality*
  • Fentanyl / analogs & derivatives
  • Fentanyl / pharmacology*
  • Fentanyl / poisoning
  • Humans
  • Muscle Rigidity / chemically induced
  • Muscle Rigidity / physiopathology
  • Naloxone / therapeutic use
  • Narcotic Antagonists / therapeutic use
  • Narcotics / pharmacology*
  • Narcotics / poisoning
  • Receptors, Opioid, mu / agonists*
  • Respiratory Insufficiency / chemically induced
  • Respiratory Insufficiency / physiopathology
  • Respiratory Muscles / physiopathology

Substances

  • Narcotic Antagonists
  • Narcotics
  • Receptors, Opioid, mu
  • Naloxone
  • carfentanil
  • Fentanyl