Vertebral Metastasis from Primary Parotid Adenocarcinoma

World Neurosurg. 2019 Jun;126:472-474. doi: 10.1016/j.wneu.2019.02.229. Epub 2019 Mar 15.


Background: Parotid adenocarcinoma comprises 10% of all parotid cancers and does not frequently produce distant metastases. The most common site for metastases is the lung, and there have only been 2 reported cases of skeletal metastases. The purpose of this study is to report the first vertebral metastasis from a primary parotid adenocarcinoma. Patient records, imaging, and pathology from a case of vertebral metastasis of a primary parotid adenocarcinoma were reviewed. A literature review of parotid adenocarcinoma metastases was also performed and is presented.

Case description: A 53-year-old male with a medical history of parotid adenocarcinoma treated with chemotherapy and radiation presented with back pain. Computed tomography and magnetic resonance imaging of the lumbar region showed a lytic lesion on the left side of the L4 vertebral body, and a biopsy confirmed the lesion was metastatic adenocarcinoma.

Conclusions: Distant metastases from a primary parotid adenocarcinoma are rare events, especially metastases to bone. This case represents the first vertebral metastasis from a primary parotid adenocarcinoma.

Keywords: Back pain; Lumbar vertebrae; Metastasis; Parotid adenocarcinoma.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / pathology*
  • Humans
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / pathology
  • Male
  • Middle Aged
  • Parotid Neoplasms / diagnostic imaging
  • Parotid Neoplasms / pathology*
  • Spinal Neoplasms / diagnostic imaging
  • Spinal Neoplasms / pathology*
  • Spinal Neoplasms / secondary*