Hypoproteinemic alkalosis

Am J Med. 1986 Jul;81(1):86-90. doi: 10.1016/0002-9343(86)90187-7.

Abstract

Hypoproteinemia by itself causes a nonrespiratory ("metabolic") alkalosis. On the average, a decrease in plasma albumin concentration of 1 g/dl produces an increase in "standard" bicarbonate of 3.4 mM/liter, and an apparent base excess of +3.7 meq/liter; it also reduces the value of the normal anion gap by about 3 meq/liter. Concentration of plasma protein should be measured as part of the analysis of acid-base status. Interpretation of acid-base data requires special consideration in "primary hypoproteinemic alkalosis."

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Alkalosis / blood
  • Alkalosis / etiology*
  • Bicarbonates / blood
  • Blood Proteins / analysis
  • Carbon Dioxide / blood
  • Chlorides / blood
  • Female
  • Humans
  • Hypoproteinemia / complications*
  • Middle Aged
  • Serum Albumin / analysis
  • Sodium / blood

Substances

  • Bicarbonates
  • Blood Proteins
  • Chlorides
  • Serum Albumin
  • Carbon Dioxide
  • Sodium