The Continuing Value of CD4 Cell Count Monitoring for Differential HIV Care and Surveillance

JMIR Public Health Surveill. 2019 Mar 20;5(1):e11136. doi: 10.2196/11136.


The move toward universal provision of antiretroviral therapy and the expansion of HIV viral load monitoring call into question the ongoing value of CD4 cell count testing and monitoring. We highlight the role CD4 monitoring continues to have in guiding clinical decisions and measuring and evaluating the epidemiology of HIV. To end the HIV/AIDS epidemic, we require strategic information, which includes CD4 cell counts, to make informed clinical decisions and effectively monitor key surveillance indicators.

Keywords: CD4; HIV; antiretroviral therapy; differential care; monitoring; surveillance.