Familial Cavernous Hemangioma

J Neuroophthalmol. 2020 Jun;40(2):262-264. doi: 10.1097/WNO.0000000000000778.


A 30-year-old woman presented with diplopia after resection of an intracranial cavernous malformation. Fundus examination showed an asymptomatic intraocular cavernous hemangioma of the retina. Clinicians should be aware of the potential coexistence of intraocular and intracranial cavernous malformations; the presence of both should suggest familial etiology. As with other intracranial and intraocular vascular lesions (e.g., arteriovenous malformation in Wyburn-Mason syndrome, retinal hemangioblastoma in von Hippel Lindau disease, and choroidal hemangioma in Sturge-Weber syndrome), the presence of a vascular lesion in either location should prompt evaluation for additional pathology.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Brain Neoplasms / diagnosis*
  • Female
  • Hemangioma, Cavernous / diagnosis*
  • Hemangioma, Cavernous, Central Nervous System / diagnosis*
  • Humans
  • Magnetic Resonance Imaging
  • Temporal Lobe / pathology*

Supplementary concepts

  • Familial cerebral cavernous malformation