Primary squamous cell carcinoma of the seminal vesicle: A case report and review of the literature

Medicine (Baltimore). 2019 Mar;98(12):e14788. doi: 10.1097/MD.0000000000014788.


Rationale: Primary squamous cell carcinoma (SCC) of the seminal vesicle is extremely rare, and the clinical characteristics of this kind of malignancy are still unclear.

Patient concerns: A 62-year-old male patient presented with complaints of sensation of rectal tenesmus and dysuria.

Diagnosis: Ultrasonography suggested a hypoechoic mass behind the bladder, meanwhile, computerized tomography (CT) and magnetic resonance imaging (MRI) revealed a 40 mm × 45 mm × 48 mm mixed solid/cystic tumorous lesion in the right seminal vesicle. Postoperative histology confirmed the diagnosis of primary SCC in the seminal vesicle.

Intervention: The mass was surgically excised with a laparoscopic approach. Postoperatively, 6 cycles of chemotherapy and 50 Gy of external beam radiation were concurrently performed on this patient.

Outcomes: No local recurrence or distant metastasis was detected within 2 years after the surgery.

Lessons: Primary SCC of the seminal vesicle is a rare neoplasm with a poor prognosis. Clinically, it is crucial to establish early precise diagnosis and apply multimodality treatment.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / surgery
  • Chemotherapy, Adjuvant / methods
  • Genital Neoplasms, Male / diagnostic imaging
  • Genital Neoplasms, Male / pathology*
  • Genital Neoplasms, Male / surgery
  • Humans
  • Laparoscopy / methods
  • Male
  • Middle Aged
  • Seminal Vesicles / diagnostic imaging
  • Seminal Vesicles / pathology*
  • Seminal Vesicles / surgery