Atrophoderma of Pasini and Pierini in a young adult: a case report

Acta Dermatovenerol Alp Pannonica Adriat. 2019 Mar;28(1):45-46.

Abstract

Atrophoderma of Pasini and Pierini is a skin atrophy presenting as single or multiple sharply demarcated, hyperpigmented, non-indurated patches, with a slight depression of the skin, that can converge and form a confluent area with atrophy as a consequence. The condition was first described by Pasini in 1923 and subsequently by Pierini in 1936. They distinguished this form of atrophy from other diseases and conditions in which the atrophy is morphologically and clinically different. The disease was initially associated with Borrelia burgdorferi infection; however, at present, various theories have emerged for the appearance of the disease, linked to genetic, neurogenetic, and immunological factors. Here we present a patient that was admitted to the hospital due to disseminated lesions on the skin of the lower limbs, with slightly pigmented and atrophic skin along with irregular borders varying in size, from several mm to a few cm, clearly demarcated from the healthy skin, with no history of a tick bite or a family history of similar skin disorders.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Atrophy / pathology
  • Atrophy / physiopathology
  • Biopsy, Needle
  • Humans
  • Hyperpigmentation / pathology*
  • Hyperpigmentation / physiopathology
  • Immunohistochemistry
  • Kosovo
  • Lower Extremity*
  • Lyme Disease / physiopathology
  • Male
  • Rare Diseases
  • Risk Assessment
  • Skin Diseases / pathology*
  • Skin Diseases / physiopathology
  • Skin Diseases / therapy
  • Young Adult