Chip-based digital polymerase chain reaction technology is useful for monitoring the JAK2 V617F allele burden in Philadelphia-negative myeloproliferative neoplasms

MeSH terms

• Adult
• Aged
• Aged, 80 and over
• Antineoplastic Combined Chemotherapy Protocols / therapeutic use
• Female
• Humans
• Hydroxyurea / administration & dosage
• Hydroxyurea / therapeutic use
• Janus Kinase 2 / genetics*
• Janus Kinase 2 / metabolism
• Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / diagnosis
• Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / drug therapy
• Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / genetics*
• Male
• Middle Aged
• Mutation, Missense*
• Nitriles
• Outcome Assessment, Health Care / methods
• Outcome Assessment, Health Care / statistics & numerical data
• Polymerase Chain Reaction / methods*
• Pyrazoles / administration & dosage
• Pyrazoles / therapeutic use
• Pyrimidines
• Young Adult