Evaluation of living donors: quo vadis for GFR criteria?

Abstract

The evaluation of potential living donors for kidney transplantation is rigorous and is facilitated by guidelines. The assessment of glomerular filtration rate (GFR) is crucial to this process. The methods of ascertaining GFR and thresholds used for determining eligibility of donors are not uniform. Measured instead of estimated GFR, and age-adapted thresholds for GFR, may provide a better assessment of donors, yielding a higher rate of acceptance while minimizing risks of permitting donation in the presence of a reduced (for age) level of GFR.