Recent advances in spontaneous intracerebral hemorrhage

F1000Res. 2019 Mar 18:8:F1000 Faculty Rev-302. doi: 10.12688/f1000research.16357.1. eCollection 2019.


Intracerebral hemorrhage (ICH) is a stroke subtype associated with significant morbidity and mortality. The purpose of this review is to provide an update on important research on ICH over the past three years. Topics covered include risk factors, imaging predictors of hematoma expansion, scoring schema to predict hematoma expansion, hemostatic therapies, acute blood pressure lowering, intraventricular administration of alteplase for intraventricular hemorrhage, and the current status of surgical therapies.

Keywords: antithrombotic reversal; blood pressure lowering; deompressive hemicraniectomy; hematoma expansion; intracerebral hemorrhage; intraventricular alteplase.

Publication types

  • Review

MeSH terms

  • Blood Pressure
  • Cerebral Hemorrhage* / diagnosis
  • Cerebral Hemorrhage* / therapy
  • Hematoma / diagnosis
  • Hematoma / etiology
  • Hematoma / therapy
  • Humans
  • Risk Factors

Grants and funding

The author(s) declared that no grants were involved in supporting this work.