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. 2019 Oct;25(11):1427-1433.
doi: 10.1177/1352458519837705. Epub 2019 Mar 25.

MOG Antibody-Associated Encephalomyelitis/Encephalitis

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Free PMC article

MOG Antibody-Associated Encephalomyelitis/Encephalitis

Sara Salama et al. Mult Scler. .
Free PMC article

Abstract

Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM). In this review, we discuss MOG-positive cases presenting with encephalitis, encephalopathy, or ADEM-like presentation based on recently published series.

Keywords: MOG antibody disease; MOG encephalomyelitis; MOG-EM; anti-MOG; myelin oligodendrocyte glycoprotein; optic neuritis; transverse myelitis.

Conflict of interest statement

Disclosures: Authors have no disclosures to report that are applicable to this study.

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