Outcome of ambulatory video-EEG monitoring in a ˜10,000 patient nationwide cohort

Seizure. 2019 Mar;66:104-111. doi: 10.1016/j.seizure.2019.01.018.

Abstract

Purpose: We evaluate outcome of in-home diagnostic ambulatory video-EEG monitoring (AVEM) performed on a nationwide cohort of patients over one calendar year, and we compare our findings with outcomes of inpatient adult and pediatric VEM performed during the same year at two academic epilepsy centers.

Methods: This is a retrospective cohort study. We obtained AVEM outcome data from an independent ambulatory-EEG testing facility. Inpatient VEM data from a 4-bed adult epilepsy center and an 8-bed pediatric epilepsy center were also included. Primary outcome measure was composite percentage of VEM records with epileptiform activity on EEG tracings or at least one video-recorded pushbutton event. We assessed patient-reported symptoms documented in AVEM event diaries.

Results: Of 9221 AVEM recordings performed across 28 states, 62.5% attained primary outcome. At least one patient-activated pushbutton event was captured on video in 54% of AVEM recordings (53.6% in adults, 56.1% in children). Epileptiform activity was reported in 1657 (18.0%) AVEM recordings (1473 [88.9%] only interictal, 9 [0.5%] only ictal, 175 [10.6%] both interictal and ictal). Most common patient-reported symptomatology during AVEM pushbutton events was behavioral/autonomic/emotional in adults and children. Compared to AVEM, inpatient VEM captured more confirmed representative events in adult and pediatric samples.

Conclusions: AVEM is useful for non-urgent diagnostic evaluation of events.

Keywords: Ambulatory EEG; EEG; Epilepsy monitoring; Video/EEG use in epilepsy.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambulatory Care / methods
  • Child
  • Cohort Studies
  • Electroencephalography / methods*
  • Epilepsy / diagnosis*
  • Epilepsy / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Monitoring, Physiologic
  • Outcome Assessment, Health Care
  • Statistics, Nonparametric
  • United States / epidemiology
  • Video Recording
  • Young Adult