Aggressive Endovascular Management of Massive Dural Venous Sinus Thrombosis in the Setting of Acute Myeloid Leukemia

Ali S Haider; Hasan Sumdani; Justin McCaslin; Ahmed Habib; Kennith F Layton

doi:10.7759/cureus.3891

Aggressive Endovascular Management of Massive Dural Venous Sinus Thrombosis in the Setting of Acute Myeloid Leukemia

Cureus. 2019 Jan 15;11(1):e3891. doi: 10.7759/cureus.3891.

Authors

Ali S Haider¹, Hasan Sumdani², Justin McCaslin³, Ahmed Habib⁴, Kennith F Layton³

Affiliations

¹ Neurosurgery, Texas A&M College of Medicine, Houston, USA.
² Neurosurgery, Texas A&M College of Medicine, Round Rock, USA.
³ Radiology, Baylor University Medical Center, Dallas, USA.
⁴ Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, USA.

Abstract

While hematologic malignancies are understood to be a risk factor for dural sinus thrombosis (DST), little data is available regarding the presentation and management of synchronous cases. In this case, a 40-year-old woman with newly diagnosed acute myeloid leukemia (AML) developed extensive DST with symptoms refractory to systemic anticoagulation. The decision was made to pursue aggressive endovascular intervention and the patient's symptoms significantly improved with minimal residual deficits. Here, we report the clinical course and complex management of this rare clinical scenario.

Keywords: acute myeloid leukemia; aml; coagulopathy; dst; dural sinus thrombosis; endovascular; interventional neuroradiology; neurosurgery; thrombectomy.

Publication types

Case Reports