Defects in cell-mediated immunity

Clin Immunol Immunopathol. 1986 Oct;41(1):1-7. doi: 10.1016/0090-1229(86)90045-0.

Abstract

Defects in cell-mediated immunity result in remarkable susceptibility to opportunistic infection in contrast to the recurrent pyogenic infections observed in children with defects in antibody-mediated immunity. The major congenital defects in T lymphocytes are presented.

MeSH terms

  • Adenosine Deaminase / deficiency
  • Ataxia Telangiectasia / immunology
  • Child
  • Child, Preschool
  • DiGeorge Syndrome / immunology
  • Disease Susceptibility
  • Humans
  • Immunity, Cellular*
  • Immunologic Deficiency Syndromes / congenital
  • Immunologic Deficiency Syndromes / enzymology
  • Immunologic Deficiency Syndromes / immunology*
  • Infant
  • Infant, Newborn
  • Infections / etiology
  • Purine-Nucleoside Phosphorylase / deficiency
  • T-Lymphocytes / immunology
  • Wiskott-Aldrich Syndrome / immunology

Substances

  • Purine-Nucleoside Phosphorylase
  • Adenosine Deaminase