TAZ Forces Lateral Inhibition

Joseph G Kern; Xaralabos Varelas

doi:10.1016/j.devcel.2019.03.006

TAZ Forces Lateral Inhibition

Dev Cell. 2019 Mar 25;48(6):748-750. doi: 10.1016/j.devcel.2019.03.006.

Authors

Joseph G Kern¹, Xaralabos Varelas²

Affiliations

¹ Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.
² Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address: xvarelas@bu.edu.

PMID: 30913406
DOI: 10.1016/j.devcel.2019.03.006

Abstract

New mechanisms by which cells communicate to specify cell fate during animal development are continuously being discovered. In a recently published article in Cell, Xia et al. (2019) identify the transcriptional regulator TAZ as a novel mediator of lateral inhibition in zebrafish oogenesis that directs cell fate through mechanical cues.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Animals
Cell Communication
Cell Differentiation
Oogenesis
Zebrafish Proteins*
Zebrafish*

Substances

Zebrafish Proteins

Abstract

Publication types

MeSH terms

Substances

Grants and funding