Gut rest strategy and trophic feeding in the acute phase of critical illness with acute gastrointestinal injury

Nutr Res Rev. 2019 Dec;32(2):176-182. doi: 10.1017/S0954422419000027. Epub 2019 Mar 28.

Abstract

Critically ill patients frequently suffer from gastrointestinal dysfunction as the intestine is a vulnerable organ. In critically ill patients who require nutritional support, the current guidelines recommend the use of enteral nutrition within 24-48 h and advancing towards optimal nutritional goals over the next 48-72 h; however, this may be contraindicated in patients with acute gastrointestinal injury because overuse of the gut in the acute phase of critical illness may have an adverse effect on the prognosis. We propose that trophic feeding after 72 h, as a partial gut rest strategy, should be provided to critically ill patients during the acute phase of illness as an organ-protective strategy, especially for those with acute gastrointestinal injury.

Keywords: Acute gastrointestinal injury; Enteral nutrition; Gut rest strategy; Trophic feeding.

Publication types

  • Review

MeSH terms

  • Critical Illness / mortality
  • Critical Illness / therapy*
  • Digestion
  • Enteral Nutrition / adverse effects
  • Gastrointestinal Diseases / physiopathology
  • Gastrointestinal Diseases / therapy*
  • Gastrointestinal Tract / physiopathology
  • Humans
  • Intensive Care Units
  • Intestinal Absorption
  • Length of Stay
  • Nutrition Therapy / adverse effects
  • Nutrition Therapy / methods*
  • Nutritional Requirements