UK Biobank, big data, and the consequences of non-representativeness

doi:10.1016/S0140-6736(18)33067-8

Comparative Study

. 2019 Mar 30;393(10178):1297.

doi: 10.1016/S0140-6736(18)33067-8.

UK Biobank, big data, and the consequences of non-representativeness

Katherine M Keyes¹, Daniel Westreich²

Affiliations

¹ Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Center for Research on Society and Health, Universidad Mayor, Santiago, Chile. Electronic address: kmk2104@columbia.edu.
² Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.

PMID: 30938313
PMCID: PMC7825643
DOI: 10.1016/S0140-6736(18)33067-8

Free PMC article

Comparative Study

UK Biobank, big data, and the consequences of non-representativeness

Katherine M Keyes et al. Lancet. 2019.

Free PMC article

. 2019 Mar 30;393(10178):1297.

doi: 10.1016/S0140-6736(18)33067-8.

Authors

Katherine M Keyes¹, Daniel Westreich²

Affiliations

¹ Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; Center for Research on Society and Health, Universidad Mayor, Santiago, Chile. Electronic address: kmk2104@columbia.edu.
² Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.

PMID: 30938313
PMCID: PMC7825643
DOI: 10.1016/S0140-6736(18)33067-8

No abstract available

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Conflict of interest statement

DW received personal fees for consulting from Sanofi-Pasteur within the past 24 months, outside of this work. KMK declares no competing interests.

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References

1. Fry A, Littlejohns TJ, Sudlow C, et al. Comparison of sociodemographic and health-related characteristics of UK Biobank participants with those of the general population. Am J Epidemiol 2017; 186: 1026–34. - PMC - PubMed
1. Biobank UK. Researchers. http://www.ukbiobank.ac.uk/scientists-3/ (accessed Dec 6, 2018).
1. Lesko CR, Buchanan AL, Westreich D, Edwards JK, Hudgens MG, Cole SR. Generalizing study results: a potential outcomes perspective. Epidemiology 2017; 28: 553–61. - PMC - PubMed
1. Westreich D, Edwards JK, Lesko CR, Cole SR, Stuart EA. Target validity and the hierarchy of study designs. Am J Epidemiol 2019; 188(2): 438–43. - PMC - PubMed
1. Westreich D, Edwards JK, Lesko CR, Stuart E, Cole SR. Transportability of trial results using inverse odds of sampling weights. Am J Epidemiol 2017; 186: 1010–14. - PMC - PubMed

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[1] Fry A, Littlejohns TJ, Sudlow C, et al. Comparison of sociodemographic and health-related characteristics of UK Biobank participants with those of the general population. Am J Epidemiol 2017; 186: 1026–34. - PMC - PubMed

[2] Fry A, Littlejohns TJ, Sudlow C, et al. Comparison of sociodemographic and health-related characteristics of UK Biobank participants with those of the general population. Am J Epidemiol 2017; 186: 1026–34. - PMC - PubMed

[3] Biobank UK. Researchers. http://www.ukbiobank.ac.uk/scientists-3/ (accessed Dec 6, 2018).

[4] Biobank UK. Researchers. http://www.ukbiobank.ac.uk/scientists-3/ (accessed Dec 6, 2018).

[5] Lesko CR, Buchanan AL, Westreich D, Edwards JK, Hudgens MG, Cole SR. Generalizing study results: a potential outcomes perspective. Epidemiology 2017; 28: 553–61. - PMC - PubMed

[6] Lesko CR, Buchanan AL, Westreich D, Edwards JK, Hudgens MG, Cole SR. Generalizing study results: a potential outcomes perspective. Epidemiology 2017; 28: 553–61. - PMC - PubMed

[7] Westreich D, Edwards JK, Lesko CR, Cole SR, Stuart EA. Target validity and the hierarchy of study designs. Am J Epidemiol 2019; 188(2): 438–43. - PMC - PubMed

[8] Westreich D, Edwards JK, Lesko CR, Cole SR, Stuart EA. Target validity and the hierarchy of study designs. Am J Epidemiol 2019; 188(2): 438–43. - PMC - PubMed

[9] Westreich D, Edwards JK, Lesko CR, Stuart E, Cole SR. Transportability of trial results using inverse odds of sampling weights. Am J Epidemiol 2017; 186: 1010–14. - PMC - PubMed

[10] Westreich D, Edwards JK, Lesko CR, Stuart E, Cole SR. Transportability of trial results using inverse odds of sampling weights. Am J Epidemiol 2017; 186: 1010–14. - PMC - PubMed

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UK Biobank, big data, and the consequences of non-representativeness

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UK Biobank, big data, and the consequences of non-representativeness

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