Tocilizumab during pregnancy and lactation: drug levels in maternal serum, cord blood, breast milk and infant serum

Rheumatology (Oxford). 2019 Aug 1;58(8):1505-1507. doi: 10.1093/rheumatology/kez100.

Authors

Jumpei Saito¹, Naho Yakuwa², Kayoko Kaneko³, Chinatsu Takai², Mikako Goto², Ken Nakajima², Akimasa Yamatani^{1

2}, Atsuko Murashima^{2

3}

Affiliations

¹ Department of Pharmaceuticals.
² Japan Drug Information Institute in Pregnancy.
³ Division of Maternal Medicine, Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.

PMID: 30945743
DOI: 10.1093/rheumatology/kez100

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antibodies, Monoclonal, Humanized / adverse effects
Antibodies, Monoclonal, Humanized / analysis*
Breast Feeding
Female
Fetal Blood / chemistry*
Humans
Infant
Infant, Newborn
Lactation
Maternal Exposure / adverse effects
Milk, Human / chemistry*
Pregnancy
Pregnancy Complications / drug therapy*
Still's Disease, Adult-Onset / drug therapy*

Substances

Antibodies, Monoclonal, Humanized
tocilizumab