Growing burden of alcoholic liver disease in China: A review

World J Gastroenterol. 2019 Mar 28;25(12):1445-1456. doi: 10.3748/wjg.v25.i12.1445.

Abstract

Explosive economic growth and increasing social openness in China over the last 30 years have significantly boosted alcohol consumption, and consequently, the incidence of alcoholic liver disease (ALD) in China has increased. Because the epidemiologic and clinical features of ALD in the Chinese population may differ from those of the Caucasian population, this review describes the epidemiology, pathogenesis, genetic polymorphisms, diagnosis, and treatment of ALD in the Chinese population. This updated knowledge of ALD in China provides information needed for a global understanding of ALD and may help in the development of useful strategies for reducing the global ALD burden.

Keywords: Alcoholic liver disease; China; Epidemiology; Morbidity.

Publication types

  • Review

MeSH terms

  • Alcohol Drinking / adverse effects
  • Alcohol Drinking / epidemiology*
  • Asian People / genetics
  • China / epidemiology
  • Cost of Illness*
  • Genetic Predisposition to Disease
  • Humans
  • Incidence
  • Liver Diseases, Alcoholic / diagnosis
  • Liver Diseases, Alcoholic / epidemiology*
  • Liver Diseases, Alcoholic / genetics
  • Liver Diseases, Alcoholic / therapy
  • Polymorphism, Genetic
  • Risk Factors
  • Socioeconomic Factors*