Factors Associated with Delayed Transition to Oral Feeding in Infants with Single Ventricle Physiology

J Pediatr. 2019 Aug:211:134-138. doi: 10.1016/j.jpeds.2019.02.030. Epub 2019 Apr 2.

Abstract

Objectives: To describe the duration of time to achieve exclusive oral feeding in infants with single ventricle physiology and to identify risk factors associated with prolonged gastrostomy tube dependence.

Study design: Single center, retrospective study of infants with single ventricle physiology. The primary outcome was duration of time required to achieve oral feeding. Transition periods were defined as exclusive oral feeding by Glenn palliation (early), by 1 year of age (mid), or after 1 year of age (late).

Results: Seventy-eight infants were analyzed; 46 (59%) were discharged to home with a gastrostomy tube after the initial hospitalization. Overall, 39 infants (50%) achieved early transition, 14 (18%) mid, and 18 (23%) late. The group who achieved early transition had a higher percentage of preoperative oral feeding (P < .01), greater weight-for-age z score at initial discharge (P = .03), shorter initial intensive care unit duration (P < .01), shorter initial hospital length of stay (P < .01), and greater weight-for-age z score at Glenn admission (P = .02). No preoperative oral feeding (OR = 0.12, P = .02) and greater number of cardiac medications at initial discharge (OR = 3.8, P = .03) were associated with failure to achieve early transition. No preoperative oral feeding (OR = 0.09, P = .01) and longer initial intensive care unit duration (OR = 1.1, P = .03) were associated with failure to achieve mid transition.

Conclusion: Preoperative oral feeding may potentially be a modifiable factor to help improve early transition to oral feeding.

Keywords: congenital; enteral nutrition; gastrostomy; heart defects.

MeSH terms

  • Body Weight
  • Cardiovascular Agents / administration & dosage
  • Cardiovascular Surgical Procedures*
  • Enteral Nutrition*
  • Female
  • Humans
  • Infant
  • Intensive Care Units, Pediatric
  • Length of Stay
  • Male
  • Oxygen / blood
  • Preoperative Care
  • Retrospective Studies
  • Time Factors
  • Univentricular Heart / surgery*

Substances

  • Cardiovascular Agents
  • Oxygen