A review: Nanofibrous scaffold in possible prevention and treatment of coronary artery disease

Biotechnol Appl Biochem. 2019 Jul;66(4):478-483. doi: 10.1002/bab.1750. Epub 2019 Apr 15.

Abstract

Nanofibrous scaffolds have potential to improve coronary stent applications by promoting endothelial recovery on the stent surface and aids regeneration of cardiac tissues. Presently, scaffolds fabricated via electro-spinning are been widely used because of their ability to bio-mimic the precise anatomical structure of the protein fibers. Properties like convenience to spin on several components and functionalization with several bioactive molecules have signify the use of nanofibrous scaffolds for tissue engineering. This review highlights some recent applications of electrospun nanofibrous scaffolds in the treatment and management of cardiac arterial diseases and engineering new cardiac tissues.

Keywords: cardiac arterial diseases; electrospun; myocardial infarction; nanofibers; scaffolds.

Publication types

  • Review

MeSH terms

  • Coronary Artery Disease / drug therapy*
  • Coronary Artery Disease / prevention & control*
  • Humans
  • Nanofibers / chemistry*
  • Tissue Engineering
  • Tissue Scaffolds / chemistry*