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, 28 (2), 491-499
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Antioxidant and Immune-Enhancing Effects of Probiotic Lactobacillus plantarum 200655 Isolated From Kimchi

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Antioxidant and Immune-Enhancing Effects of Probiotic Lactobacillus plantarum 200655 Isolated From Kimchi

Seo-Jin Yang et al. Food Sci Biotechnol.

Abstract

Probiotic properties including antioxidant and immune-enhancing effects of Lactobacillus plantarum 200655 isolated from kimchi were evaluated. The tolerance of three strains (L. plantarum 200655, L. plantarum KCTC 3108, and L. rhamnosus GG to bile salts (0.3% oxgall, 24 h) was similar, and L. plantarum 200655 showed the highest tolerance to gastric juice (0.3% pepsin, 3 h). All strains presented similar autoaggregation ability. L. plantarum 200655 showed higher cell surface hydrophobicity and adhesion ability on HT-29 cells. L. plantarum 200655 did not produce β-glucuronidase and was sensitive to ampicillin, tetracycline, chloramphenicol, and doxycycline. Additionally, L. plantarum 200655 showed the highest antioxidant effects in DPPH and ABTS radical scavenging, and β-carotene bleaching assays. RAW 264.7 cells treated with L. plantarum 200655 produced more nitric oxide, induced nitric oxide synthase, and cytokine related to immune-enhancing effects such as interleukin-1β and interleukin-6. Therefore, L. plantarum 200655 could be useful as a probiotic strain for older people.

Keywords: Antioxidant activity; Immune-enhancing effect; Kimchi; Lactobacillus plantarum; Probiotics.

Conflict of interest statement

Compliance with ethical standardsThe authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Immune-enhancing effects of LAB strains on RAW.264.7 cells. (A) Nitric oxide expression (μM); relative intensity of (B) iNOS, (C) IL-1β, (D) IL-6, and (E) TNF-α expression. LPS(−), non-treated; LPS(+), 10 ng/mL of lipopolysaccharide-treated; GG, L. rhamnosus GG-treated; 655, L. plantarum 200655-treated; 3108, L. plantarum KCTC 3108-treated. Different letters on each bars indicate significant difference between values (p < 0.001)

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