Current Epidemiology, Etiology, and Burden of Acute Skin Infections in the United States

Keith S Kaye; Lindsay A Petty; Andrew F Shorr; Marya D Zilberberg

doi:10.1093/cid/ciz002

Current Epidemiology, Etiology, and Burden of Acute Skin Infections in the United States

Clin Infect Dis. 2019 Apr 8;68(Suppl 3):S193-S199. doi: 10.1093/cid/ciz002.

Authors

Keith S Kaye¹, Lindsay A Petty¹, Andrew F Shorr², Marya D Zilberberg^{3

4}

Affiliations

¹ Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor.
² Health Services Research, Washington Hospital Center, Washington, DC.
³ Division of Pulmonary and Critical Medicine, EviMed Research Group, LLC, Goshen.
⁴ Division of Pulmonary and Critical Medicine, University of Massachusetts School of Public Health and Health Sciences, Amherst.

Abstract

The US burden of acute skin infections is substantial. While Staphylococcus aureus and Streptococcus spp. are the most common causes, gram-negative bacteria and mixed infections can occur in some settings. These mixed infections are more likely to result in inappropriate empiric antibiotic therapy. Important challenges remain in diagnosing and treating acute skin infections.

Keywords: United States; acute bacterial skin and skin structure infections; burden; epidemiology; etiology.

Publication types

Review

MeSH terms

Acute Disease
Anti-Bacterial Agents / pharmacology
Anti-Bacterial Agents / therapeutic use
Cost of Illness*
Disease Management
Disease Susceptibility
Humans
Public Health Surveillance
Risk Factors
Skin Diseases, Bacterial / diagnosis
Skin Diseases, Bacterial / epidemiology*
Skin Diseases, Bacterial / microbiology*
Skin Diseases, Bacterial / therapy
Soft Tissue Infections / diagnosis
Soft Tissue Infections / epidemiology
Soft Tissue Infections / microbiology
Soft Tissue Infections / therapy
Treatment Outcome
United States / epidemiology

Substances

Anti-Bacterial Agents