[THE STUDY OF PHYSICAL - CHEMICAL AND TECHNOLOGICAL PROPERTIES OF EPIMEDIUM STRELOLIST'S DRY EXTRACT TO CREATE A SOLID DOSAGE FORM FOR THE TREATMENT OF ERECTILE DYSFUNCTION]

Georgian Med News. 2019 Feb;(287):137-140.
[Article in Russian]

Abstract

One of the most famous aphrodisiac plants and remedy for recoveryerectile dysfunction is Estrellita Epimedium (Epimedium sagittatum). On this basis, development of the new dosage form (capsules with dry extract of Epimedium strelolist) is one of the promising directions in phytotherapy of erectile dysfunction in men. The main task in development of a new dosage form is the study of the physical-chemical and technological active pharmaceutical substance's (API) characteristics, such as crystal form, solubility, flowability, angle of repose, tap density, water. In this study, the dry extract of Epimedium strelolist is an API. Research of above characteristics will determine the choice of excipients and technology of dosage form.

MeSH terms

  • Chemistry, Pharmaceutical*
  • Crystallization
  • Dosage Forms
  • Drugs, Chinese Herbal
  • Epimedium / chemistry*
  • Erectile Dysfunction / drug therapy*
  • Excipients*
  • Humans
  • Male
  • Pharmaceutical Preparations / chemistry*
  • Phytotherapy
  • Plant Preparations
  • Technology, Pharmaceutical*

Substances

  • Dosage Forms
  • Drugs, Chinese Herbal
  • Excipients
  • Pharmaceutical Preparations
  • Plant Preparations