The Bacterivore's Solution: Fight and Flight to Promote Survival

Yi-Tang Lee; Meng C Wang

doi:10.1016/j.devcel.2019.03.021

The Bacterivore's Solution: Fight and Flight to Promote Survival

Dev Cell. 2019 Apr 8;49(1):7-9. doi: 10.1016/j.devcel.2019.03.021.

Authors

Yi-Tang Lee¹, Meng C Wang²

Affiliations

¹ Integrative Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX 77030, USA; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.
² Integrative Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX 77030, USA; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: wmeng@bcm.edu.

PMID: 30965036
DOI: 10.1016/j.devcel.2019.03.021

Abstract

Bacterial avoidance and innate immune response are two ways by which C. elegans respond to pathogenic bacteria. In this issue of Developmental Cell, Kumar et al. (2019) and Singh and Aballay (2019) demonstrate that bacterial colonization is essential to induce both responses, which may be associated with somatic and reproductive longevity.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Animals
Caenorhabditis elegans Proteins*
Caenorhabditis elegans*
Immunity, Innate
Longevity
Signal Transduction

Substances

Caenorhabditis elegans Proteins

Abstract

Publication types

MeSH terms

Substances

Grants and funding