Neurofibromatosis in pregnancy. Four case reports and review of the literature

Isr J Med Sci. 1986 Jul-Aug;22(7-8):579-81.

Abstract

Neurofibromatosis (Recklinghausen's disease) is an autosomal dominant disorder that affects multiple organ systems. The disease usually manifests itself during puberty although it occasionally occurs during infancy and childhood. Pregnancy seems to exacerbate the condition. Four cases of neurofibromatosis during pregnancy are presented. Three of the patients had uneventful pregnancies and deliveries, and the fourth had severe thrombocytopenia. This complication has not previously been reported in association with neurofibromatosis in pregnancy. By close supervision of pregnant patients with neurofibromatosis, most complications can be avoided.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Hypertension / etiology
  • Male
  • Neurofibromatosis 1* / complications
  • Pregnancy
  • Pregnancy Complications / etiology
  • Pregnancy Complications, Neoplastic*
  • Thrombocytopenia / etiology