Injection of N‑butyl Cyanoacrylate Through a Dual-Lumen Balloon for Embolization of High-flow Intranidal Fistulas in Brain Arteriovenous Malformations: Technical Note

Clin Neuroradiol. 2020 Jun;30(2):313-319. doi: 10.1007/s00062-019-00780-6. Epub 2019 Apr 10.

Abstract

Purpose: N-butyl cyanoacrylate (NBCA) glue is a valuable liquid embolic agent for the endovascular treatment of brain arteriovenous malformations (BAVM). The use of NBCA carries a risk of embolic agent reflux and distal migration with ensuing possibility of venous drainage compromise. The aim of this technical note is to describe a single center case series of high-flow intranidal fistulas embolized though a dual lumen balloon under local flow-arrest conditions.

Methods: This article presents a retrospective description of a case series including five NBCA injections through a dual lumen balloon performed by a single operator in three patients with BAVM. Demographic, clinical, imaging and procedure-related data are reported.

Results: The three patients presented with ruptured BAVMs. Of the patients, one underwent proximal flow-related ruptured aneurysm coiling before planned BAVM embolization. In the three patients, staged BAVM embolization as a first line treatment was decided. Preliminary embolization of high-flow BAVM fistulas by NBCA using a dual lumen balloon under local flow-arrest conditions was performed and five separate injections were carried out without any complications. No balloon entrapment or rupture was observed.

Conclusion: High-flow BAVM fistulas can be treated with NBCA embolization using a dual lumen balloon under local flow-arrest conditions.

Keywords: Arteriovenous malformation; Dual lumen balloon; Embolization; Fistula; N-butyl cyanoacrylate.

MeSH terms

  • Adult
  • Aged
  • Drug Administration Routes
  • Embolization, Therapeutic / methods*
  • Enbucrilate / administration & dosage
  • Enbucrilate / therapeutic use*
  • Female
  • Humans
  • Intracranial Arteriovenous Malformations / complications*
  • Intracranial Arteriovenous Malformations / therapy*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Vascular Fistula / complications*
  • Vascular Fistula / therapy*

Substances

  • Enbucrilate